Impacto do uso de corticoides a nível hospitalar na sobrevida de pacientes com COVID-19
DOI:
https://doi.org/10.47224/revistamaster.v7i14.297Keywords:
SARS-COV-2, Corticosteroides, Dexametasona, Hidrocortisona, Prednisolona×Abstract
Given the current controversies regarding the treatment of hospitalized patients with COVID-19, it is necessary to
analyze articles regarding the use of corticosteroids to determine whether the risks of this therapy outweigh its
benefits. In Brazil, a higher incidence was identified in Mato Grosso and Rio de Janeiro, with a confirmed total of more
than 25 million and lethality around 2.5%. The present study was developed in order to carry out a survey of the
literature and verify the most used drug options in terms of their effectiveness. The clinical use of corticosteroids was
identified, which proved to be not so effective, but necessary and lack clinical follow-up to assess the risk and benefit.
Randomized controlled clinical trials of early administration of a low to moderate dose of methylprednisolone to
COVID-19 patients with ARDS are needed to confirm the efficacy and safety of corticosteroid therapy and to further
study long-term outcomes after discharge.
Keywords: SARS-CoV-2, Corticosteroids, Dexamethasone, Hydrocortisone, Prednisolone.
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